在这部浩劫惊魂动作/冒险/剧情片中,尼克是一名军事系统的设计师，为了报复公司的冷漠无情，于是他决定窃取了一块包含顶尖技术出售给境外的黑帮迪米屈。
阿曼达是联邦调查局的女特工，她卧底潜入迪米屈黑帮内部已一年多了，准备伺机将迪米屈缉拿归案。然而，当她察觉尼克与迪米屈正在交易时，冒着不惜暴露自己身份的危险，将尼克的银行帐户密码替换了，并且乘混乱之际将他逮捕了。
然而一个难题又出现在她的面前，她的上级指示要将尼克送往洛杉矶....
Epicenter concerns brassy, beautiful Amanda Foster, a down-on-her-luck San Francisco F.B.I. Agent who's been assigned to protect a Computer Hacker-turned-State's-Witness, Nick Constantine, from the mob. On the Day of the assignment, the city is rocked by a devastating earthquake, forcing Amanda and Nick to fight their way through the ravaged city streets while being pursued by ruthless assassins and a corrupt F.B.I. Agent.
