在这部不受欢迎之家喜剧/动画片中,在位于东京·中野的合租房中共同生活的，有家主纽手（Himote）家三姐妹时世、纪奈美、心，以及心的同学多惠和美奈萌，还有家里养的猫小缘。
以通称“不受欢迎之家（Himote House）”为舞台，个性丰富的成员们每天烦恼着“要如何才能变得受欢迎？”的同时热闹地度日，稍显稚嫩的女生共同生活喜剧。
实际上这5人和1只，拥有不可思议的力量……
From Kotaro Ishidate, creator of some popular ad-lib animes. The new anime centers on five girls and one cat all living as housemates in Nakano: the three Himote sisters (Tokiyo, Kinami, and Kokoro) whose family manages the "Himote House," Kokoro's classmates Tae and Minamo, and the cat Enishi.
