在这部夜行神龙电影版动画/动作/犯罪片中,剧情叙述公元994年的苏格兰城堡，有一群帮助人类捍卫城堡的夜行神龙，他们日间为石像、夜间为神龙，由Goliath所领导。但是却因为人类的阴谋，神龙们几乎被摧毁殆尽。仅存的神龙虽然躲过一劫，但却沉睡了千年之久。当他们醒来时发现世界已经变了，他们如今身处在纽约曼哈顿的现代都会，是由百万富翁 Xanatos将整个城堡移建过来，他希望这群神龙能为他所用。但是历经人类背叛险遭灭族的夜行神龙，如今还会再度相信人类吗？
In 994 A.D., Goliath and the few remaining gargoyles help defend the Scottish castle where they live. In exchange the human occupants protect the gargoyles during the day, since they turn to stone from dawn to dusk. The gargoyles are put under a spell, and they remain in stone form for one thousand years. When they wake up they find that their castle has been moved atop a skyscraper in New York city, thanks to billionaire Xanatos. He wants their help, but the gargoyles are leary of treachery. Meanwhile Goliath forms a friendship with Elisa Maza, a police detective who is investigating Xanatos.
